Breast cancer- Newest updates

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Breast cancer refers to the cancer in the breast, and is commonly found in women.

The main treatments of breast cancer are commonly surgery, radiation, chemotherapy, hormone therapy and targeted therapy. But medical science continues to study better treatments and drugs along with new combinations of existing treatments.

It is established now that breast cancer can be divided into subtypes that respond differently to various types of treatment.

The three main clinically known subtypes are:

Hormone receptor (HR) positive- The breast cancers are those which contain the estrogen receptor (ER) and/or progesterone receptor (PR). These cancers grow in response to these hormones and can be treated with hormone therapies. 

Human epidermal growth factor receptor 2 (HER2) positive- The cancers that have high amounts of the HER2 protein; they can be HR positive or negative. The treatment would include therapies that target HER2.

Triple-negative breast cancer- These are the cancers that do not contain ER, PR or HER2.


Genomic analyses, such as those carried out through The Cancer Genome Atlas (TCGA) have helped reveal the molecular diversity of breast cancer and eventually could help identify further breast cancer subtypes. This knowledge can lead to more advanced treatment methods that target the genetic alterations that drive those cancer subtypes.


As for HR-positive breast cancer treatments, targeted therapy uses drugs or other substances to attack cancer cells with less harm to normal cells. A new focus, that is present. Is on adding targeted therapies to hormone therapy for advanced or metastatic HR-positive breast cancer. These treatments could prolong the time until chemotherapy is needed and ideally, extend survival.





Doctors specializing in this field can provide intricate guidance on the cases. One should always be aware and look out for symptoms which may seem like nothing at first but can turn to worse, if ignored.
Mentionable names among some of the Best Oncologists in Kolkata are: Dr. Sanjoy Roy and Dr. Sayan Paul.

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