Parkinson’s diseases

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Parkinson’s disease is referred to as a progressive nervous system disorder that affects movement. Symptoms are noticed gradually, sometimes starting with barely a tremor in just one hand. Although tremors are common the disease usually causes stiffness or slowing of movement.


In the early stages of the disease, your face may start losing expressions, your arms may not swing when you walk, speech may be slurred or soft and the symptoms worsen as your condition worsens over time. Unfortunately, Parkinson's disease has no cure, but medications may make significant improvements. Sometimes, doctors may suggest surgery to regulate certain regions of the brain and improve your symptoms.


Parkinsosn’s disease: what happens and why?

Parkinson’s disease involves breakage of certain nerve cells or neurons. Many of the symptoms are due to a loss of the neurons that produce dopamine, a chemical messenger in the brain. When dopamine levels decrease, it causes abnormal brain activities, leading to impaired movements and other symptoms of the parkinson’s disease.


Although the cause of the disease are known, several factors appear to play a role:

  1. Genes: study has identified specific genetic mutations that can cause the disease, but these are uncommon except in rare cases with multiple family members affected with parkinson’s disease.

  2. Environmental triggers: Exposure to certain toxins or environmental factors may increase the risk of later development of Parkinson’s disease, but the risk is comparatively small. Among all the changes, a few notable ones are:

    1. The presence of Lewy bodies, which are referred to the clumps of specific substances within the brain cells, are markers of Parkinson's disease. Researchers deem these Lewy bodies hold an important clue to the cause of Parkinson’s disease.

    2. Alpha-synclein found within the Lewy bodies is one of the most important one among others and is the natural and widespread protein called alpha-synuclein. This is currently an important focus among the researchers of this disease.




A senior neurosurgeon of international repute with excellent management skills and one of the Best Neurosurgeons in Kolkata, Dr. Kaushik Sil has over 16 years of experience in treating complex Brain and Spine problems like brain tumours, spinal disc prolapse, brain stroke, subdural hematoma, spinal deformity with a special interest in childhood neurosurgical problems like hydrocephalus and spinal birth defects. His simple guidance and high success in treatment rates is immaculate.

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